Judging by a tweet from developer Gearbox, a Borderlands 3 revel could be on the horizon. The tweet shows a picture of a street sign presumably on Borderlands primarily-desert planet Pandora showing a date of March 28 and location of Boston, Massachusetts, the time and location of Gearbox's PAX East panel. The environment is stylized like Borderlands' cel-shaded style, with the sign saying exit 3.
We'll know for sure in a few weeks. Here’s hoping its actually Borderlands 3 and not a another remaster or something like that.